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主营:蛋白质分泌细胞的体外检测试剂
℡ 4000-520-616
℡ 4000-520-616
U-CyTech/mAb anti-mouse IL-2 (clone S4B6-1)/0.5 mg/CT336
产品编号:CT336
市  场 价:¥4640.00
场      地:美国(厂家直采)
产品分类: 抗体类>一抗>流式抗体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$232.00
品      牌: U-CyTech
公      司:U-CyTech
公司分类:
U-CyTech/mAb anti-mouse IL-2 (clone S4B6-1)/0.5 mg/CT336
商品介绍
Catalogue Number
CT336
Description
mAb anti-mouse IL-2 (clone S4B6-1) - 0.5 mg
Price
€232.00
Characteristics
clone S4B6-1
Summary
The rat anti-mouse IL-2 monoclonal antibody (clone S4B6-1) is of the IgG2a subtype and neutralizes both natural and recombinant mouse IL-2 in vivo (Chaudhri G. et al. 2004). Zurawski S. et al. 1986 used the S4B6-1 antibody in Western blot analysis. Their analysis showed that the determinant recognized by S4B6-1 requires the N-terminal region of mouse IL 2 and there was no cross reaction with human IL-2. The S4B6-1 antibody is also applicable in immunohistochemistry on frozen tissues, intracellular staining, FACS analysis and immunoprecipitation (Chaudhri G. et al. 2004, Assenmacher M. et al. 1998 and Mosmann T. et al. 1990).

References list

  • Sequential production of IL-2, IFN-gamma and IL-10 by individual staphylococcal enterotoxin B-activated T helper lymphocytes.
    Assenmacher, M, et al. Eur. J. Immunol. 1998 May;28: 1534-43
  • Polarized type 1 cytokine response and cell-mediated immunity determine genetic resistance to mousepox.
    Chaudhri, Geeta, et al. Proc. Natl. Acad. Sci. U.S.A. 2004 Jun 15;101: 9057-62
  • Two types of mouse helper T cell clone. III. Further differences in lymphokine synthesis between Th1 and Th2 clones revealed by RNA hybridization, functionally monospecific bioassays, and monoclonal antibodies.
    Cherwinski, H M, et al. J. Exp. Med. 1987 Nov 01;166: 1229-44
  • A tumor-associated and self antigen peptide presented by dendritic cells may induce T cell anergy in vivo, but IL-12 can prevent or revert the anergic state.
    Grohmann, U, et al. J. Immunol. 1997 Apr 15;158: 3593-602
  • Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.
    Mosmann, T R, et al. J. Immunol. 1986 Apr 01;136: 2348-57
  • Isolation of monoclonal antibodies specific for IL-4, IL-5, IL-6, and a new Th2-specific cytokine (IL-10), cytokine synthesis inhibitory factor, by using a solid phase radioimmunoadsorbent assay.
    Mosmann, T R, et al. J. Immunol. 1990 Nov 01;145: 2938-45
  • Induction of IgG2a class switching in B cells by IL-27.
    Yoshimoto, Takayuki, et al. J. Immunol. 2004 Aug 15;173: 2479-85
  • Alterations in the amino-terminal third of mouse interleukin 2: effects on biological activity and immunoreactivity.
    Zurawski, S M, et al. J. Immunol. 1986 Nov 15;137: 3354-60
品牌介绍

u-cytech Biosciences公司成立于1999与乌特列支大学合作的生物科技公司和位于乌得勒支的荷兰(欧洲)。该家族企业以开放的政策和众多忠实的顾客从事细胞因子生物学的基础研究和应用研究,致力于在ELISA和T、B细胞的ELISPOT检测而设计的个别蛋白质分泌细胞的体外检测。此外,我们开发的“房子”一个广泛的高度特异的单克隆抗体和多克隆抗体的蛋白质包括不同的物种形成了我们高度敏感的检测的基础上(ELISA、ELISPOT、FluoroSpot)。

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